Ph.D., Catholic University of America, 1973.
Phone: (787)764-0000 ext. 7581, 4884.
Fax. (787) 764-2610
Field of Interest: Oncology: Motile Response of Cancer Cells to Extracellular Matrix
Components and Autocrine Motility Factors
Studies to determine the role of arachidonic acid metabolites in the chemotactic and
haptotactic response of A2058 human melanoma cells to extracellular matrix components
(EMC's) such as fibronectin, laminin and collagen Type IV.
Additional studies include the role of autocrine motility factors secreted by cancer
cells on these cells and other cells.
Effects of up-regulators of cadherins in preventing cell motility in response to
autocrime motiligy factors, are also investigated. The information obtained will help in
understanding the mechanisms which influence cancer metastasis in order to design
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Inhibition of Hepatic Catalase. J. of Clinical Biotechnology 2: 100-106.
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and Treatment. Third International Symposium. Academic Press, London, pp. 173-193.
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on Liver Catalase Activity in Mice. J. Gen. Microbiol. 130: 119-122.